This paper presents a comparison of the ionospheric propagation factor M(3000)F2 measurements with IRI-2016 model predictions at Thailand low latitude station, namely Chiang Mai (18.76°N, 98.93°E, dip angle 12.7°N). The M(3000)F2 data in 2016 are scaled from the ionograms recorded by the ionosonde measurements. The hourly values of M(3000)F2 are analyzed based on the diurnal, seasonal, annual variations and compared with the IRI model predictions. Both observed and IRI model data showed similar variations in that decreasing from pre-sunrise to noontime hours (3-12LT), and increasing from afternoon time to post-midnight hours (13-03LT) with a few decreasing during post sunset hours (20-00LT). Furthermore, most of the results show the IRI model data gave the M(3000)F2 values close to the observed data during daytime and it underestimated the measured ones during nighttime. All of these studies have important effect on the development of future IRI-model for Southeast Asia.