Two common approaches to tractography seeding are using the whole-brain white matter
mask, or the gray and white matter interface. Using a dataset with two acquisitions per
subject and a state of the art processing pipeline, we compared the test-retest reproducibility
of the shape and tract profiles of major white matter bundles for both seeding strategies. We
found that both seeding strategies have regions in the brain where they are more
reproducible. We propose an ensemble method combining both strategies as a possible …