Multipath TCP (MPTCP), which enables the use of multiple wireless links (e.g., Wi-Fi and LTE) for data transmissions, is an excellent technology for evolving multi-homing devices in mobile wireless networks. This paper explores concepts and feasibility of realizing MPTCP with path awareness (PA), in which the path-aware information is leveraged to reinforce the MPTCP transmissions. In particular, when aware of a network situation, a device can facilitate a mechanism that dynamically shifts the MPTCP traffic to a single path and vice versa. As a result, MPTCP with PA could solve the significant problem of negative aggregation benefit when the MPTCP throughput over divergent paths is worse than the best one of single-path TCP. We illustrate the feasibility of the proposed concept through our new implementation of a so-called MPTCP-LA (i.e., MPTCP with Loss Awareness). MPTCP-LA keeps the aggregation benefits non-negative by temporarily switching an MPTCP transmission on a path to a standby condition when the on-device observed loss reaches a threshold. We extensively evaluate MPTCP-LA in comparison to the standard MPTCP in an emulated environment. The results show that MPTCP-LA has better performance regarding enhancing throughput and saving networking resources.