Genetic manipulation of protein levels is a promising approach to identify the function of a
specific protein in living organisms. Previous studies demonstrated that the auxin-inducible
degron strategy provides rapid and reversible degradation of various proteins in fungi and
mammalian mitotic cells. In this study, we employed this technology to postmitotic neurons to
address whether the auxin-inducible degron system could be applied to the nervous system.
Using adeno-associated viruses, we simultaneously introduced enhanced green fluorescent …