The134th KARC Colloquium

Date&Time	26 December 2018(Thu) 13:30-15:00
Place	Conference Room, 3F, Research Building 2, Advanced ICT Research Institute
Lecturer	How myosins move
Speaker	Prof. Peter Knight University of Leeds, UK
Abstract	What are the mechanisms used by proteins that function as motors to move cargoes inside cells or to produce external movements such as muscle contraction and the beating of flagella? What are the principles by which activity is regulated in these systems? How is the complex macromolecular complex of the muscle myofibril assembled and how does turnover of protein molecules occur within it? To address these questions, Dr. Knight is running research projects focusing on ‘Mechanisms of regulation of myosin activity’, ‘Properties and roles of single stable alpha helical domains’, and ‘Molecular mechanism of dynein’. In this colloquium, Dr. Knight is going to give a talk about ‘How myosins move’ which covers their recent work on the mechanism of myosin-5 stepping and on the role of its stable single-alpha helices (SAH) domains.
Language	English
Admission	Free
Organizer	Hiroaki Kojima, General Manager, Frontier Creative Research Laboratory, Frontier Creative Research laboratory, KARC, NICT